BOLD Portal (authorized personnel only)


BOLD Registry: We reached the recruitment goal of 5000 subjects. We closed the recruitment at all three sites: Kaiser Permanente Northern California and Harvard Vanguard Medical Associates. We continue to follow-up with subjects.

LESS RCT: We completed recruitment into the RCT. 400 subjects were randomized at sixteen sites: Brigham and Women’s Hospital, Harvard Vanguard Medical Associates, Massachusetts General Hospital and St. Elizabeth’s Medical Center in Boston, Henry Ford Health System with West Bloomfield Center in Detroit, Kaiser Permanente Northern California at Redwood City, San Jose, Roseville and Martinez, the University of Colorado in Denver, Mayo Clinic in Rochester, OHSU in Portland, Stanford University in Redwood City, Virginia iSpine Physicians in Richmond and the VA Medical Center in Dallas. The follow-ups are continuing.



The BOLD Project is supported by grant number 1R01HS019222-01 from the
Agency for Healthcare Research and Quality (AHRQ)